Recombinant DNA Technology

Recombinant DNA (rDNA) technology is the field of molecular biology that scientists "Edit" to select DNA molecules of new synthetic, which is often referred to as "illusion". Exercise cut it, paste copy the DNA and return to repeat successful Arthur Kornberg to viral DNA breakthrough was the proof of concept, reproduction. This was followed by Swiss Werner Arber Biochemistry discovery of restriction enzymes in bacteria that lead to deterioration of the external viral DNA molecules, while sparing their DNA. Stacy showed the effectiveness of such genes can be "cut" DNA molecules, soon to follow up and understanding that can be used to ligase 'glue' together. These achievements launched two rDNA technology and research, and allow the man to "play God" for the first time in human history. Also discussed between the activists storm as Jérémie Rifkin, who use terms like "cloning" and the image conjured Recombinant DNA scientists' rogue running amok, and the creation of Frankensteins and used to evil purposes, or worse, and loss of control creations.
However, these problems when I shut scholars such as Paul Berg, who won the Nobel Prize in 1980 for his pioneering work in research rDNA, halted trials can be dangerous, so the policy can deal with dilemmas resulting from new technological opportunities. In the Asilomar conference in 1975, came from the foremost experts recombinant DNA together in Monterey, California, agreed that there should be safeguards to prevent any health crises or environmental disasters, and to reassure the public that their research will go forward with caution.
Other landmarks in the development of recombinant DNA involves collaboration between Stanley Cohen and Herbert Boyer, in 1972 and in 1976 from Genentech established the first company that works with rDNA in drug testing laboratories in their development. In 1978 scientists are able to repeat somatostatin, a protein that regulates human growth hormones. Since then, a group of other drugs through research rDNA, including Herceptin Epogen.
So how does one go about making a molecule rDNA? There are three basic ways: conversion, [Glenn] Introduction and bacterial transformation. Regardless of the method used and the goal is the introduction of recombinant genes in host cell with the agent of expression, so that the host cell for the desired protein. In any case, scientists need to "stop" signal that tells the host cells for destruction or degradation of the introduced genes.

Recombinant DNA research is a field challenge, but has great promise for the future. In the future, rDNA technology will play a key role in the prevention of genetic diseases and production of drugs targeted, and provide patients with less toxic drugs. It will also affect agriculture, livestock, and researchers find ways to improve the genetic codes of plants and animals to resist disease. Even so, also raises serious questions rDNA. We are equipped to deal with the environmental impact of the rDNA molecule has lost its way, for example, genetically modified plants and spreading beyond the expulsion of native species? Is a good job of parents to 'choose' genetic traits they want a child? What is the impact of such decisions will have on society as a whole?

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